Cortisone 및 Calcium이 국소마취약의 Acetylcholine 근련축억제효과에 미치는 영향
배유홍, 함종대, 이상신,
소속 상세정보
배유홍 ( Baei Yu-Hong ) - 서울대학교 치과대학
함종대 ( Hahm Jhong-Dai ) - 서울대학교 대학원 치의학과 보존학
이상신 ( Lee Sang-Shin ) - 서울대학교 대학원 치의학과
KMID : 0362719740120060419
Abstract
The authors have investigated the roles of cortisone and calcium on the depressive effects of local anesthetics on the acetylcholine-induced skeletal muscle contraction in frog. The results are as follows. 1. Tetracaine, cocaine, lidocaine and procaine decreased the acetylcholine-induced skeletal muscle contraction. 2. Cortisone increased the depressive effects of local anesthetics on the acetyl-choline-induced skeletal muscle contraction. 3. There was a tendency that in high calcium concentration, the depressive effects of cocaine and lidocaine on acetylcholine-induced skeletal muscle contraction were increased.
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